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Blue - Bluepharma Magazine

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Brochures

Institutional Brochure

With eyes set on the future

17/05/2023.8.9 MB

Development & Manufacturing

Your partner that cares

25/04/2023.7.6 MB

Product Portfolio

Development and Licensing Opportunities

25/04/2023.8.3 MB

Value Added Medicines

Oromucosal Delivery, Complex Steriles and OSD Fixed-Dose Combinations

25/04/2023.6.1 MB

ONConcept®

A strategic collaboration in the field of oncology

11/10/2022.5.8 MB

Scientific Publishing

Oromucosal products – Market landscape and innovative technologies: A review

Francisca Bastos, Ana Catarina Pinto, António Nunes, Sérgio Simões

07/06/2022

Molecular structure, spectroscopy and photochemistry of alprazolam

13/08/2021

Hot-Melt Extrusion: a Roadmap for Product Development

16/06/2021

Medication adherence in older people with rheumatoid arthritis is lower according to electronic monitoring than according to pill count

03/03/2021

GMP-grade nanoparticle targeted to nucleolin downregulates tumor molecular signature, blocking growth and invasion, at low systemic exposure

15/02/2021

Amphiphilic well-defined degradable star block copolymers by combination of ring-opening polymerization and atom transfer radical polymerization: Synthesis and application as drug delivery carriers

18/01/2021

Artificial neural networks applied to quality-by-design: From formulation development to clinical outcome

18/05/2020

Enhanced solid-state stability of amorphous ibrutinib formulations prepared by hot-melt extrusion

16/02/2020

Quality by design in pharmaceutical manufacturing: A systematic review of current status, challenges and future perspectives

17/12/2019

Five-Stage Approach for a Systematic Screening and Development of Etravirine Amorphous Solid Dispersions by Hot-Melt Extrusion

27/11/2019

Hot-melt extrusion in the pharmaceutical industry: toward filing a new drug application

24/05/2019

Orphan drugs: major development challenges at the clinical stage

15/01/2019

Critical process parameters of orodispersible films (ODFs)

13/02/2018

Intradermal Delivery of a Near-Infrared Photosensitizer Using Dissolving Microneedle Arrays

31/05/2018

Increasing the Bile Acid Sequestration Performance of Cationic Hydrogels by Using an Advanced/Controlled Polymerization Technique

15/06/2017

Retrospective Quality by Design (rQbD) applied to the optimization of orodispersible films

16/06/2017

A first in human study using photodynamic therapy with Redaporfin in advanced head and neck cancer

30/04/2017

Ultrafast Dynamics of Manganese(III), Manganese(II), and Free-Base Bacteriochlorin: Is There Time for Photochemistry?

16/02/2017

The use of liposomes for the systemic delivery of RNAi therapeutics aiming at cancer treatment

15/01/2016

Outlining critical quality attributes (CQAs) as guidance for the development of orodispersible films

26/06/2016

Hydrophobic polymers for orodispersible films: a quality by design approach

29/03/2016

Nucleolin overexpression in breast cancer cell sub-populations with different stem-like phenotype enables targeted intracellular delivery of synergistic drug combination

05/08/2015

Intravenous Single-Dose Toxicity of Redaporfin-Based Photodynamic Therapy in Rodents

08/12/2015

Mucoadhesive oral films: The potential for unmet needs

23/08/2015

Elimination of primary tumours and control of metastasis with rationally designed bacteriochlorin photodynamic therapy regimens

25/06/2015

Oral films: Current status and future perspectives II — Intellectual property, technologies and market needs

14/03/2015

Oral films: Current status and future perspectives: I — Galenical development and quality attributes

05/03/2015

Polymeric bile acid sequestrants—Synthesis using conventional methods and new approaches based on “controlled”/living radical polymerization

17/09/2012

Simultaneous active intracellular delivery of doxorubicin and C6-ceramide shifts the additive/antagonistic drug interaction of non-encapsulated combination

10/10/2014

Manufacturing and export provisions: Impact on the competitiveness of European pharmaceutical manufacturers and on the creation of jobs in Europe

08/10/2014

Photodynamic Therapy Efficacy Enhanced by Dynamics: The Role of Charge Transfer and Photostability in the Selection of Photosensitizers

18/03/2014

Modulation of Biodistribution, Pharmacokinetics, and Photosensitivity with the Delivery Vehicle of a Bacteriochlorin Photosensitizer for Photodynamic Therapy

27/12/2013

Efficient intracellular delivery of siRNA with a safe multitargeted lipid-based nanoplatform

28/08/2013

Targeted and intracellular triggered delivery of therapeutics to cancer cells and the tumor microenvironment: impact on the treatment of breast cancer

29/07/2011

Toward a siRNA-containing nanoparticle targeted to breast cancer cells and the tumor microenvironment

18/05/2012

Lipid-Based Nanoparticles for siRNA Delivery in Cancer Therapy: Paradigms and Challenges

07/05/2012

Combined effects of singlet oxygen and hydroxyl radical in photodynamic therapy with photostable bacteriochlorins: Evidence from intracellular fluorescence and increased photodynamic efficacy in vitro

13/01/2012

Development, Characterization and In Vitro Evaluation of Single or Co-Loaded Imatinib Mesylate Liposomal Formulations

30/04/2012

Tissue Uptake Study and Photodynamic Therapy of Melanoma-Bearing Mice with a Nontoxic, Effective Chlorin

04/07/2011

Biodistribution and Photodynamic Efficacy of a Water-Soluble, Stable, Halogenated Bacteriochlorin against Melanoma

24/01/2011

Schedule treatment design and quantitative in vitro evaluation of chemotherapeutic combinations for metastatic prostate cancer therapy

08/04/2010

Targeting non-viral vectors to tumor cells and the tumor microenvironment

23/09/2010

Co-encapsulation of anti-BCR-ABL siRNA and imatinib mesylate in transferrin receptor-targeted sterically stabilized liposomes for chronic myeloid leukemia treatment

13/07/2010

Synthesis and photophysical characterization of a library of photostable halogenated bacteriochlorins: an access to near infrared chemistry

11/10/2010

New Halogenated Water-Soluble Chlorin and Bacteriochlorin as Photostable PDT Sensitizers: Synthesis, Spectroscopy, Photophysics, and in vitro Photosensitizing Efficacy

15/08/2010

Mechanisms of Singlet-Oxygen and Superoxide-Ion Generation by Porphyrins and Bacteriochlorins and their Implications in Photodynamic Therapy

29/07/2010

Liposomal imatinib–mitoxantrone combination: Formulation development and therapeutic evaluation in an animal model of prostate cancer

23/11/2010

Ciprofloxacin sensitizes hormone-refractory prostate cancer cell lines to doxorubicin and docetaxel treatment on a schedule-dependent manner

23/12/2008

Synthesis and photophysical properties of amphiphilic halogenated bacteriochlorins: new opportunities for photodynamic therapy of cancer

30/09/2009

Non-Viral Lipid-Based Nanoparticles for Targeted Cancer Systemic Gene Silencing

30/04/2008

Synthesis of amphiphilic sulfonamide halogenated porphyrins: MALDI-TOFMS characterization and evaluation of 1-octanol/water partition coefficients

21/03/2008

Cationic liposomes for gene delivery

11/05/2005

Targeting of sterically stabilised pH-sensitive liposomes to human T-leukaemia cells

23/11/2004

On the formulation of pH-sensitive liposomes with long circulation times

26/01/2004

Non-ligand polypeptide and liposome complexes as intracellular delivery vehicles

06/12/2001

The Gloria Adherence Subproject: Problems and Randomization Mistakes

17/10/2021

Blue - Bluepharma Magazine

Blue is made thinking about our stakeholders, intending to reflect the evolution and achievements of Bluepharma over 20 years. An annual bilingual publication in Portuguese and English, which is available in dynamic digital format (with integrated links and videos) and in print format.